t6ert 47ebd r5n2h 7z7zz 2zf8r 55s22 3et6z bysf2 yzs8i 368zr tib3f sta8e 32ifs 7hbnr 38be7 n73ks d64ey 92d9z h3hy7 3se46 zs532 Ball-park estimate on in-breeding (human) |

Ball-park estimate on in-breeding (human)

2022.01.25 07:51 teh_saccade Ball-park estimate on in-breeding (human)

This is a question for anyone, and please be aware that it is for fiction, not anything real.
It is common knowledge that inbreeding (esp. along familial lines) can lead to genetic issues that are detrimental to the species, whether it be dogs, rats, bats or humans.
What I am asking for here is a guesstimate on how long it may be (in human terms) for the human race to have exhausted the gene pool we have, before it becomes necessary to either:
a) modify genes in parents / correct defects in offspring (gestation or later). b) introduce breeding policies to avoid known pathways to error. c) require additional diversity (eg, genetically modified parentage / other species / races).
For example, there is an island with no contact outside (use christmas as an exmple) and within several generations - everyone can trace their lineage back to christmas adam and christmas eve. As generations progress, more and more become it becomes apparent that genetic aberrations are negative issues, and very few are what would be called, I suppose, evolutionary mutations.
In such a small community as 1000 individuals - if the population is limited to a terminus by space and resources available to 1 million - there comes a point in my simulation whereby the family trees, rather than continuing to branch out, start to branch inwards as the % number of couplings that result in children non-viable starts to collapse the population.
It results in a diamond-shaped tree.
Please be aware that I am running a very basic simulation with a very set % of issues when particular 1,2,3,4 sequences are met by both parents, and constant rate of reproduction.
I know that this is not realistic, but consider it a thought-game and project ourselves, evolved monkeys stuck on a ball of rock, falling through space...
It may be aeons, but that is the scale I am working with for the story spans over many aeons.
While some authors such as Stephen Baxter have the human race evolving over such vast distances in time, into beings that adapt to their environment (evolving into consciousness supported along cosmic strings, I think was the end-point in that short story) - I have not found one that deals with overcoming the "limited" gene pool that we have being trapped on earth, with the resources (and gene-altering influences, from diet to drugs to direct exposure) that we do.
Is anyone willing to throw a few numbers at me, with a short reason as to why they believe this would be..?
Even if it is, "never"..?
Thank you!
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2022.01.25 07:51 Ice-Guardian What is it called you intentionally do things to hurt yourself?

Not strictly self-harm, but I don't think it's masochism either.
For example, I play ice hockey and I hate it when I don't get hurt, and purposefully don't wear some gear so I get hurt worse... It's not that I "enjoy" pain exactly, but I feel the need to cause pain "accidently" like at work when I might put my finger in front of my box knife (I don't cut it, I have a fear of blood) just to "accidently" cut it... It makes me feel alive, and actually don't like how pain feels actually... It's hard to explain.
At times, i have hurt myself ice skating and was limping for a few weeks but still refused to stop going weekly and kept injuring it more everytime I fell on it again. But here's the weird part: I try to hide it from other people and wouldn't limp in front of them but whenever I was alone I would actually play it up and limp more just becauae... It's as though it's the complete opposte to Munchausen Syndrome, I don't do it for attention at all but I can't help but keep thinking "why does no one ask about it?" even though I purposefully don't show it in front of people... Where's the logic in that?
Is there a psychological term that explains that?
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2022.01.25 07:51 Lukonas I heard my GF masturbating

The other day I heard that my girlfriend was masturbating in the bathroom. I'm usually chill about this stuff, but the fact that for the last 2-3 weeks she didn't want to have any sexual intimacy with me makes me question if she even wants me or is she into me. I asked her multiple times if she did masturbate and she said no every time. Should I be concerned about it?
Also the other day we were playing with cards and she said she would like to do the strip-off challenge, but not all the way (not until naked, just until you reach your underwear and bra) also she would like to do it with her friend group and without me. Knowing the fact that she didn't show any intimacy (apart from simple kisses) to me for the last 2-3 weeks should I also be concerned about this?
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Ik, Ik y'all are tired of these but I need to know. Looking for a first 1 mil vehicle so Drone, Volt (don't really want it) or Blackhawk?
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2022.01.25 07:51 ixSASA Is It worth it returning after Jan update ?

I dropped the game once I played and got everything I wanted before 2 months. Now with the current news about dungeon difficulties and other major stuff, is it worth it ?
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2022.01.25 07:51 CryptoCryptonaire ReadySwap Sustainability?

Can someone please explain to me how ReadySwap can sustain? At this time, the READY token is worth $.09, so the entire 40,000 supply can be bought for under $4,000 dollars. How can the pools or farms continue giving out READY?
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They have MM in their name but the textures look more realistic.. anyone who has downloaded their cc, how does it look in game without editings https://mmfinds.tumblr.com/post/674273979031257088/s4cc-mmsims-ilsan-skirt-shoes
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2022.01.25 07:51 Scarlet_Jedi I really want 1:1 replica....DISNEYLAND???

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When someone touches me, like a friendly grab in the arm or a teasing pinch (nothing painful but with enough force) the area aches for a minute or two like i have a bruise, then it goes away. What is it? It makes me stray away from friendly physical contact with friends because i dont like the ache. I have had this for maybe a year
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2022.01.25 07:51 heytherehowsu Your Local Friendly Pakistani Brown boy thats more White than Brown Needs a Friend And you know What Lets make it Longterm While we're at it 21/M

My Nose is Red and i have the Flu, I'll do Anything to spend more Time with You
You are Shit and i am the Sweeper, why dont we make this Relationship a little bit Deeper
Local Pakistani guy here in my early 20s Lookin for good long term friends and yes i did come up with those rhymes all by myself in a matter of seconds, if you do become my friend maybe i'll write a custom poem for you, trust me people have laughed and cried while laughing reading them
so yeah hit me up in the dms or message me and lets get the friendship thing started
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2022.01.25 07:51 CarbonDemontizide How do I make use of wii music in the format of .xa and .xam.

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